Tower Hamlets let a two-goal lead slip to suffer a 3-2 loss to Cannons Wood in Thurlow Nunn League Division One South on Saturday.
Solomon Asomah netted his eighth goal of the campaign and Connor French was also on target to put Kiernan Hughes-Mason's side on top at Mile End Stadium, raising hopes of only their second win of the campaign.
But Daniel Jones hit back with a brace for the visitors and Reece Simpson was also on target to leave Hamlets empty-handed once again.
Asomah had netted a hat-trick in a 4-1 Hamlets win over Southend Manor a week earlier, with substitute Craig Heskey also on target.
But defeat at the weekend left them three points adrift at the bottom of the table and, after a Tuesday night trip to Enfield Borough, they head out into the Essex countryside to take on Burnham Ramblers on Saturday.
Hamlets then return to home turf on Wednesday (September 20) to play host to their east London rivals Clapton, who upset high-flying Hutton 2-1 on Saturday to make it back-to-back wins.
Fellow Mile End Stadium tenants Sporting Bengal United, meanwhile, are due to entertain Little Oakley in the Essex Senior League on Saturday.
They came from behind to draw 1-1 with unbeaten West Essex last week, thanks to an injury-time goal from Chaka Barnett.
And it was a similar story at the weekend as they fell behind at Stanway Rovers - as former captain Freddy Tandon netted against his old club - before Sheri Artmeladze netted an 85th-minute equaliser.
That left them in fourth place as they prepared to welcome Takeley last night (Wednesday).
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